Shanghai AI Lab, together with Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, has released the medical multimodal foundational model group 'PuYi 2.0'. PuYi 2.0 adds multi-domain models and incremental language parameters, covering various data modalities such as medical images, medical texts, and bioinformatics. New open-source datasets include the medical image segmentation dataset SA-Med2D-20M and the pathology dataset SNOW. PuYi 2.0 incorporates an evaluation module to provide reference implementations for medical model capabilities, delivering a one-stop open-source solution for large medical models.